Non-Toxic Flavonoids of Artemisia annua can be used as Anti-Cancer Compounds: A Computational Analysis

Objective: To identify potential flavonoids of Artemisia annua effective against cancer using computationalapproaches.Study Design: Computational approaches were used to predict the anticancer activity throughCDRUG, comparing it with standard drug, followed by determining physiochemical propertiesand toxicity prediction selected flavonoids.Place and Duration Study: The study was carried out at Department Bioinformatics Biosciences ofCapital University Science Technology (CUST) Islamabad, from December 2017 July 2018.Materials Methods: L downloaded computational techniques such as similarity search, prediction, targets identification etc. applied investigate their anti-cancer activities.Results: Luteoline, Cirsilineol, Cirsiliol, Eupatorin, Crisimaritin Artemetin showed positive results among allthe tested flavonoids. These compounds have replace drugs because anti-canceractivity, cells approved agents.Conclusion: screened are good candidate for future be cancer. However,this is an in-silico requiring further laboratory enzymatic assays confirmation, which can done invitro in future.